The Voltage rating on a fuse denotes the value that will not be carried by arcing across a blown fuse. For instance, if you had a 12 Volt rated fuse, and installed it in a 10,000 Volt circuit, if the fuse blew, the gap developed by the over current would not be large enough to prevent the 10,000 Volts from arcing over the gap.
There are fuses that have different Voltage ratings for DC and AC. I'd Google the current and Voltage of the circuit you wanted to protect, and look at the results from vendors.
TTFN,
Dennis