Unfortunately the controller's +5V supply has a very low current output which I would expect to be 50~100mA max
(0.05~0.1A) so it cannot be used to operate a 12V horn.
A conventional 12V electromagnetic type car horn will draw a fair amount of current
(typically 5~10 Amps) which would still be too much for the majority of cheap DC-DC converters, but something like this
120 Watt 48V to 12V DC-DC converter should produce enough current for a single 12V horn, but you would need to check the current draw if using a dual horn
(twin tone) set-up.
In addition to this, you would also require suitable higher current wiring as the existing wiring to and from the horn switch is much too thin.
However, it should be possible to use a
48V relay to enable the existing horn switch to operate the horn by momentarily switching battery voltage to the DC-DC converter which would have its 12V output wired directly to the horn.
Alan